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Table 4 Diagnostic performance of plasma-calprotectin cut-offs for transfer to ICU/HD among patients with infection

From: Plasma calprotectin as an indicator of need of transfer to intensive care in patients with suspected sepsis at the emergency department

Calprotectin cut-off value (mg/L)

Sensitivity a

Specificity b

Positive predictive value c

Negative predictive value d

2

70 (46/66)

52 (131/253)

25 (46/185)

86 (122/142)

2.5

61 (40/66)

66 (155/253)

29 (40/138)

86 (155/181)

3

53 (35/66)

70 (177/253)

31.5 (35/111)

85 (177/208)

3.5

48.5 (32/66)

76 (192/253)

34 (32/93)

86 (192/226)

4

42.5 (28/66)

83 (209/253)

39 (28/72)

85 (209/247)

4.5

38 (25/66)

84 (212/253)

38 (25/66)

84 (212/253)

  1. a % (No. of true-positive cases/all cases transferred to ICU/HDU)
  2. b % (No. of true-negative cases/all cases not transferred to ICU/HDU)
  3. c % (No. of true-positive cases/all cases above cut-off)
  4. d % (No. of true-negative cases/all cases under cut-off)