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Table 3 Pooled diagnostic odds ratio, number needed to diagnose, and likelihood ratios

From: Is it time to re-think FAST? A systematic review and meta-analysis of Contrast-Enhanced Ultrasound (CEUS) and conventional ultrasound for initial assessment of abdominal trauma

 

Pooled diagnostic odds ratio (95% CI)

Pooled Numbers needed to diagnose (95% CI)

Positive likelihood ratio (95% CI)

Negative likelihood ratio (95% CI)

Conventional ultrasound

 OVERALL

60.4

(60.1–60.7)

1.297

(1.256–1.342)

20.55

(20.14–20.96)

0.41

(0.36–0.45)

 Liver

285.3

(284.5–286.2)

1.126

(1.076–1.181)

82.51

(80.53–84.48)

0.29

(0.17–0.40)

 Kidneys and adrenals

122.4

(121.2–123.6)

1.199

(1.086–1.338)

49.07

(47.34–52.80)

0.67

(0.61–0.72)

 Spleen

143.7

(142.8–144.7)

1.189

(1.119–1.269)

51.41

(49.43–53.40)

0.43

(0.33–0.53)

 Pancreas

2.7

([−1.4]–6.7)

21.450

([−2.674]–2.141)

1.45

(0.78–2.13)

0.55

([−0.80]–1.89)

 Abdominal free fluid

92.0

(91.8–92.9)

1.038

(1.001–1.077)

14.68

(14.04–15.33)

0.21

(0.02–0.41)

 Active bleeding

0.8

([−2.1]–3.7)

51.723

([−13.523]–8.880)

1.42

([−2.28]–5.12)

0.98

(0.84–1.13)

 Solid organ injury

50.9

(49.9–51.9)

1.545

(1.388–1.743)

26.22

(24.77–27.66)

0.52

(0.40–0.63)

 Composite

5.5

(5.1–6.0)

2.918

(2.368–3.801)

2.70

(2.44–2.96)

0.50

(0.32–0.67)

Contrast-enhanced ultrasound

 OVERALL

3036.9

(3036.3–3037.5)

1.038

(1.030–1.046)

125.68

(124.99–126.37)

0.07

([−0.04]–0.19)

 Liver

4926.4

(4924.8–4927.9)

1.029

(1.009–1.049)

378.43

(375.38–381.47)

0.06

([−0.22]–0.34)

 Kidneys and adrenals

6195.5

(6193.4–6197.5)

1.026

(1.005–1.048)

759.97

(745.46–765.47)

0.10

([−0.10]–0.30)

 Spleen

7142.2

(7140.5–7143.9)

1.025

(1.004–1.046)

201.14

(199.07–203.21)

0.03

([−0.45]–0.50)

 Pancreas

21.0

(16.6–25.4)

3.225

(1.89–11.013)

253.00

(246.44–259.56)

0.04

([−0.78]–0.86)

 Abdominal free fluid

29,568.0

(29,564.9–29,571.1)

1.012

(0.994–1.030)

613.47

(606.97–619.98)

0.03

([−0.55]–0.62)

 Active bleeding

350

(347.1–352.9)

1.113

(0.961–1.321)

733.62

(720.3–746.93)

0.35

(0.24–0.46)

 Solid organ injury

6330

(6327.9–6332.1)

1.034

(1.022–1.047)

205.16

(203.04–207.28)

0.03

([−0.70]–0.76)

 Composite

233.3

(232.5–234.2)

1.207

(1.172–1.244)

16.07

(15.61–16.53)

0.08

([−0.45] –0.61)