Incidence rate and topography of intra-pelvic arterial lesions associated with high-energy blunt pelvic ring injuries: a retrospective cohort study

Table 5 Factors associated with PRBC transfusion requirement during the first 24 h

	*Univariate analysis*			*Multivariable analysis*^a
Variables	OR	95% CI	p-value	OR	95% CI	p-value
IPAL (ref. no arterial lesion)	5.81	1.73–19.49	0.004	4.53	1.23–16.66	0.023
Hemodynamic instability (ref. none)	28.50	8.85–91.74	< 0.001	–	–	–
Female gender (ref. male)	0.69	0.33–1.45	0.331	0.81	0.37–1.79	0.610
Age in categories (ref. 16–39 years)			0.696			0.763
40–49	0.53	0.18–1.55	0.247	0.53	0.17–1.68	0.284
50–69	0.93	0.39–2.23	0.868	0.89	0.35–2.26	0.811
≥ 70 years	1.00	0.31–3.21	0.999	0.87	0.24–3.07	0.825
ISS, continuous	1.17	1.11–1.24	< 0.001	–	–	–
ISS ≥25 (ref. < 25)	14.63	5.87–36.47	< 0.001	–	–	–
AO/OTA classification (ref. A)			0.077	–	–	–
B	1.13	0.43–2.92	0.808
C	3.38	0.99–11.46	0.051
Young and Burgess classification (ref. NC)			0.367			0.688
LC	1.04	0.39–2.76	0.937	0.94	0.34–2.58	0.907
APC	1.86	0.50–6.94	0.356	1.31	0.30–5.77	0.723
VS & CM	2.39	0.67–8.51	0.179	1.87	0.48–7.24	0.365

^a Hosmer-Lemeshow test, p = 0.589. The variance inflation factors (VIF) are all below 1.2, suggesting no collinearity
After adjustment for sex and age, the presence of an IPAL was significantly associated with greater odds of PRBC transfusion independently of the types of PRI. Neither ISS nor hemodynamic instability was introduced in the regression model as both these factors were on the causal pathway from IPAL to transfusion
OR: odds ratio; 95% CI: 95% confidence interval; IPAL: intra-pelvic arterial lesion; ISS: Injury Severity Score; NC: not classifiable; LC: lateral compression; APC: anteroposterior compression; VS: vertical shear; CM: combined mechanism

ISSN: 1471-227X