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Table 1 Demographical and clinical conditions of the patients before preoxygenation

From: Comparison of hypoxemia, intubation procedure, and complications for non-invasive ventilation against high-flow nasal cannula oxygen therapy for patients with acute hypoxemic respiratory failure: a non-randomized retrospective analysis for effectiveness and safety (NIVaHIC-aHRF)

Parameters

Cohorts

Comparisons between cohorts

NIV

HCO

Procedure for oxygenation and ventilation

Non-invasive ventilation

High-flow nasal cannula oxygen

Patients included in the analysis

154

161

p-value

Age (years)

 Minimum

28

27

0.377

 Maximum

68

67

 Mean ± SD

57.12 ± 11.14

58.22 ± 10.91

Sex

 Male

105 (68)

107 (66)

0.811

 Female

49 (32)

54 (34)

Body-mass index (kg/m2)

25.52 ± 1.11

25.22 ± 1.85

0.084

Simplified Acute Physiology Score II

53 ± 13

50 ± 15

0.059

Sepsis-related Organ Failure Assessment score

8.12 ± 4.35

9.01 ± 4.61

0.079

Underlying chronic lung disease

42 (27)

51 (32)

0.459

Upper airway tract cancer history

6 (4)

4 (2)

0.531

Reason for the intensive care unit admission

 Respiratory infection

54 (35)

61 (38)

0.392

 Chronic obstructive pulmonary disease exacerbation

10 (7)

11 (7)

 Extra-pulmonary acute respiratory distress syndrome.

15 (10)

12 (7)

 Pulmonary atelectasis

5 (3)

3 (2)

 Shock

42 (27)

57 (35)

 Cardiogenic pulmonary edema

15 (10)

8 (5)

 Neurologic conditions

13 (8)

9 (6)

Vasopressor support at inclusion

28 (18)

31 (19)

0.885

Bilateral pulmonary infiltrates

77 (50)

82 (51)

0.911

Respiratory rates (breaths/ min)

61 ± 9

62 ± 8

0.298

The partial pressure of arterial oxygen to fraction of inspired oxygen ratio

 Mild hypoxemia (201–300 mmHg)

34 (22)

35 (22)

0.889

 Moderate-to-severe hypoxemia (≤200 mmHg)

120 (78)

126 (78)

  1. Constant variables are reported as frequency (percentages) and continuous and ordinal variables are reported as mean ± standard deviation (SD)
  2. For constant variables the Fischer exact test and for continuous and ordinal variables the Mann-Whitney U-test was performed for statistical analysis
  3. A p-value of less than 0.05 was considered significant
  4. Fraction of inspired oxygen = 0.21 + oxygen flow rate × 0.03