Table 2 Age- adjusted relationships between time-sensitive diagnosis and sex, previous history, time intervals, and clinical observations on arrival of PENs, as well as age itself, among unique patients with a final diagnosis
| Â | Â | Time-sensitive diagnosis | Â | Â | |
|---|---|---|---|---|---|
All patients (n = 3794)a | Yes (n = 487) | No (n = 3307) | Age adjusted | ||
p | OR (95% CI) | ||||
Age | 79 (53,91) | 80 (61,91) | 79 (52,91) | 0.02 | Â |
  < =65 | 753 (19.8) | 72 (14.8) | 681 (20.6) |  | 1 |
 66–80 | 1327 (35.0) | 183 (37.6) | 1144 (34.6) |  | 1.51 (1.13,2.02) |
  > 80 | 1714 (45.2) | 232 (47.6) | 1482 (44.8) |  | 1.48 (1.12,1.96) |
Male sex | 1746 (46.0) | 239 (49.1) | 1507 (45.6) | 0.11 | 1.17 (0.96,1.41) |
Dyspnoea (319)* | 2867 (82.5) | 324 (76.2) | 2543 (83.4) | < 0.0001 | 0.58 (0.46,0.75) |
Ischemic heart disease (21) | 1017 (27.0) | 149 (30.7) | 868 (26.4) | 0.16 | 1.17 (0.94,1.44) |
Heart failure (19) | 1163 (30.8) | 159 (32.7) | 1004 (30.5) | 0.78 | 1.03 (0.84,1.27) |
Hypertension | 1905 (50.2) | 280 (57.5) | 1625 (49.1) | 0.007 | 1.32 (1.08,1.61) |
Diabetes | 796 (21.0) | 130 (26.7) | 666 (20.1) | 0.002 | 1.41 (1.13,1.76) |
Atrial fibrillation (1) | 1168 (30.8) | 116 (23.8) | 1052 (31.8) | < 0.0001 | 0.59 (0.47,0.75) |
Pulmonary disease (72) | 1537 (41.3) | 127 (26.5) | 1410 (43.5) | < 0.0001 | 0.45 (0.36,0.56) |
Renal disease (1) | 465 (12.3) | 79 (16.2) | 386 (11.7) | 0.01 | 1.40 (1.08,1.83) |
System disease (4) | 270 (7.1) | 30 (6.2) | 240 (7.3) | 0.32 | 0.82 (0.55,1.22) |
Cancer (8) | 767 (20.3) | 88 (18.1) | 679 (20.6) | 0.09 | 0.80 (0.63,1.03) |
Psychiatric disorder (11) | 615 (16.3) | 62 (12.8) | 553 (16.8) | 0.06 | 0.76 (0.58,1.02) |
Pain (178) | 913 (25.2) | 127 (28.4) | 786 (24.8) | 0.06 | 1.24 (0.99,1.55) |
Syncope (18) | 53 (1.4) | 15 (3.1) | 38 (1.2) | 0.0005 | 2.95 (1.60,5.42) |
Respiratory rate < 8 or > 25 (breaths/min)(81) | 2020 (54.4) | 345 (72.3) | 1675 (51.8) | < 0.0001 | 2.38 (1.92,2.95) |
Oxygen saturation < 90 (%) (74) | 1446 (38.9) | 282 (59.5) | 1164 (35.9) | < 0.0001 | 2.56 (2.10,3.13) |
Systolic blood pressure < 90 (mmHg)(133) | 84 (2.3) | 25 (5.4) | 59 (1.8) | < 0.0001 | 3.03 (1.87,4.89) |
Heart rate < 40 or > 120 (beats/min)(80) | 488 (13.1) | 116 (24.6) | 372 (11.5) | < 0.0001 | 2.59 (2.04,3.28) |
Body temperature < 35.0 or > 41.0 (°C)(129) | 23 (0.6) | 8 (1.8) | 15 (0.5) | 0.002 | 3.95 (1.66,9.42) |
Degree of consciousness (RLS) > 2 (694) | 67 (2.2) | 31 (8.1) | 36 (1.3) | < 0.0001 | 6.55 (3.99,10.74) |
Pathological ECG (284) | 1110 (31.6) | 243 (52.6) | 867 (28.4) | < 0.0001 | 2.76 (2.26,3.37) |
Time from symptom onset to call (193) | 58 (1340) | 27 (0,223) | 62 (1341) | < 0.0001 |  |
  < =12 h | 1076 (29.9) | 185 (41.1) | 891 (28.3) |  | 1 |
 12–24 h | 179 (5.0) | 22 (4.9) | 157 (5.0) |  | 0.66 (0.41,1.06) |
 24–48 h | 320 (8.9) | 36 (8.0) | 284 (9.0) |  | 0.60 (0.41,0.88) |
 48–72 h | 391 (10.9) | 54 (12.0) | 337 (10.7) |  | 0.75 (0.54,1.04) |
  > 72 h | 1635 (45.4) | 153 (34.0) | 1482 (47.0) |  | 0.49 (0.39,0.61) |
Time from call to PENs arrival (51) | 18 (9,51) | 15 (8,43) | 18 (9.51) | < 0.0001 |  |
 0–6 min | 90 (2.4) | 18 (3.8) | 72 (2.2) |  | 1 |
 7–12 min | 929 (24.8) | 155 (32.5) | 774 (23.7) |  | 0.79 (0.46,1.36) |
 13–24 min | 1527 (40.8) | 176 (36.9) | 1351 (41.4) |  | 0.51 (0.30,0.88) |
  > 24 min | 1197 (32.0) | 128 (26.8) | 1069 (32.7) |  | 0.47 (0.27,0.81) |