|  | AMI (n = 255) | No AMI (n = 845) | Total (n = 1100) | Proportion Negative Test | Sensitivity | NPV |
---|---|---|---|---|---|---|---|
Hs-cTnI 99th percentile threshold: ECG positive or hs-cTnI ≥16 ng/L (females) and ≥34 ng/L (males) | Positive | 223 | 126 | 349 |  | 89.9 (85.5 to 93.1) |  |
Negative | 25 | 705 | 730 | 67.7 | Â | 96.6 (95.0 to 97.7) | |
Hs-cTnI or H-FABP 99th percentile threshold: ECG positive or hs-cTnI ≥16 ng/L (females) or ≥34 ng/L (males) or H-FABP ≥ 3.6 ng/mL | Positive | 243 | 442 | 685 |  | 98.0 (95.4 to 99.1) |  |
Negative | 5 | 389 | 394 | 36.5 | Â | 98.7 (97.1 to 99.5) | |
Hs-cTnI 99th percentile with H-FABP ROC deriveda: ECG positive or hs-cTnI ≥16 ng/L (females) or ≥34 ng/L (males) or H-FABP ≥ 3.1 ng/mL | Positive | 245 | 511 | 756 |  | 98.8 (96.5 to 99.6) |  |
Negative | 3 | 320 | 323 | 29.9 | Â | 99.1 (97.3 to 99.7) |